Comparison of patients for the dichotomized leptomeningeal collateral score
| Characteristics | Collateral Score 3 (n = 34) | Collateral Score 0–2 (n = 53) | Effect Sizea (95% CI) | P Valueb |
|---|---|---|---|---|
| Baseline characteristics | ||||
| Male sex | 16 (47%) | 34 (64%) | 2.013 (0.844–4.802) | .127 |
| NIHSS score, median (IQR) | 15.5 (11–20) | 18 (14–22) | 2 (0–5) | .116 |
| Hypertension | 18 (53%) | 22 (42%) | 1.585 (0.671–3.745) | .379 |
| Diabetes | 3 (9%) | 8 (15%) | 0.544 (0.146–2.067) | .517 |
| Dyslipidemia | 10 (29%) | 16 (30%) | 0.964 (0.381–2.442) | <.999 |
| AF | 10 (30%) | 19 (36%) | 0.746 (0.299–1.863) | .643 |
| CAD | 6 (18%) | 5 (9%) | 2.057 (0.606–6.975) | .327 |
| Previous stroke or TIA | 4 (12%) | 9 (17%) | 0.652 (0.195–2.204) | .556 |
| Process-of-care characteristics | ||||
| IV-tPA | 22 (65%) | 18 (34%) | 3.565 (1.455–8.729) | .008 |
| IA-tPA | 2 (6%) | 11 (21%) | 0.239 (0–1.042) | .070 |
| Onset to CTAc (min) (median) (IQR) | 90 (63–124) | 90 (75–137) | 4 (−12–24) | .651 |
| Recanalizationd (min) (median) (IQR) | 146 (86.5–274) | 175 (128.68–276.5) | −32.5 (−72–14) | .169 |
| TICI 2b-3 | 25 (74%) | 35 (66%) | 1.429 (0.552–3.696) | .488 |
Note:—IA-tPA indicates intra-arterial tissue plasminogen activator; AF, atrial fibrillation; CAD, coronary artery disease.
↵a Effect sizes reported as odds ratios for categoric variables and Hodges-Lehman median differences for continuous variables (age, NIHSS score, and time-to-event data).
↵b P values reported using the Fisher exact test for categoric variables and the Wilcoxon-Mann-Whitney rank sum test for continuous variables (age, NIHSS score, and time-to-event data).
↵c Symptom onset or from the time when the patient was last seen neurologically well to the time of CTA.
↵d Time from symptom onset or from the time when the patient was last seen neurologically well to the time of intervention with any form of intra-arterial therapy.