Mean (standard deviation) of susceptibility values of different ROIs between healthy control subjects and patients with thalassemia and P values for group effect with the use of the general linear model after controlling for effects of age and sex
| PT | GP | CN | DN | SN | RN | CP | |
|---|---|---|---|---|---|---|---|
| Control subjects (10−2 ppm) | 1.82 (0.40) | 8.23 (1.24) | 2.04 (0.41) | 4.94 (1.19) | 7.42 (1.35) | 5.75 (1.63) | 3.00 (0.63) |
| Patients (10−2 ppm) | 1.91 (0.63) | 6.58 (2.23) | 2.04 (0.62) | 4.55 (1.81) | 6.33 (1.37) | 6.67 (2.52) | 7.17 (4.55) |
| P value | .248 | <.001 | .842 | .246 | .003 | .021 | <.001 |
Note:—Significantly lower susceptibility value was found in patients with thalassemia compared with healthy control subjects in GP and SN; significantly higher susceptibility value was found in patients with thalassemia in RN and CP.
PT indicates putamen; GP, globus pallidus; CN, caudate nucleus; DN, dentate nucleus; SN, substantia nigra; RN, red nucleus; CP, choroid plexus.