Fully automatic measurements of the normalized WMF, GMF, CSFF, NF, and BPF of the control group and the MS groupa
| WMF (%) | GMF (%) | CSFF (%) | NF (%) | BPF (%) | |
|---|---|---|---|---|---|
| Contr1 | 41.4 ± 2.6 | 45.5 ± 1.9 | 11.2 ± 3.1 | 2.0 ± 0.5 | 88.8 ± 3.1 |
| Contr2 | 41.3 ± 2.4 | 45.4 ± 1.8 | 11.1 ± 3.1 | 2.2 ± 0.9 | 88.9 ± 3.1 |
| MS1 | 32.9 ± 5.4 | 45.2 ± 3.0 | 18.0 ± 4.1 | 3.8 ± 1.7 | 82.0 ± 4.1 |
| MS2 | 34.0 ± 6.8 | 44.5 ± 4.6 | 17.1 ± 4.2 | 4.4 ± 1.6 | 82.9 ± 4.2 |
| Diff Contr1-Contr2 | −0.1 ± 0.9 | −0.1 ± 0.8 | 0.0 ± 0.3 | 0.2 ± 0.8 | 0.0 ± 0.3 |
| Diff MS1-MS2 | 1.1 ± 2.9 | −0.7 ± 3.2 | −1.0 ± 0.5c | 0.6 ± 0.8b | 1.0 ± 0.5c |
| Diff Contr1-MS1 | −8.4 ± 6.1c | −0.4 ± 3.4 | 6.9 ± 5.1c | 1.9 ± 1.5c | −6.9 ± 5.1c |
| Diff Contr2-MS2 | −7.3 ± 6.9c | −0.9 ± 4.3 | 6.0 ± 5.1c | 2.2 ± 1.4c | −6.0 ± 5.1c |
Note:—Diff indicates difference; Contr, control group; MS, MS patient group; 1, measurement 1; 2, measurement 2; WMF, WM fraction; GMF, GM fraction; CSFF, CSF fraction; NF, remaining, unclassified non-WM/GM/CSF tissue fraction; BPF, brain parenchymal fraction.
↵a Each tissue fraction corresponds to the tissue volume divided by the ICV. The mean value and SD are given as well as the mean difference and SD of the first measurement and the second measurement and between the controls and patients with MS.
↵b P < .05 (significant difference).
↵c P < .005 (significant difference).