Signal abnormalities related to subject age, sex, CM, and parenchymal atrophy
| Signal Abnormality | No Signal Abnormality | Total | P′ | OR (95% CI)a | P″ | |
|---|---|---|---|---|---|---|
| Total No. | 26b | 167c | 193d | |||
| Demographics | ||||||
| Age | 7.3 ± 5.5 [5.1–9.5] | 11.4 ± 6.6 [10.4–12.4] | 10.8 ± 6.6 [9.9–11.8] | .003 | 0.84 (0.76–0.94) | .001 |
| Female | 10 (38.5%) | 75 (44.9%) | 85 (44%) | .538 | 0.94 (0.32–2.83) | .918 |
| Associated abnormalities | ||||||
| Focal atrophy | 5 (17.8%) | 3 (1.8%) | 8 (4.1%) | <.001 | 17.1 (2.52–117) | .004 |
| CM | 5 (19.2%) | 7 (4.2%) | 12 (6.2%) | .003 | 19.3 (2.95–126) | .002 |
| Location | .260 | .589 | ||||
| Lobar | 24 (92.3%) | 129 (77.2%) | 153 (79.3%) | 1.0 | ||
| Thalamus/BG | 0 (0%) | 6 (3.6%) | 6 (3.1%) | 0 (0–∞) | ||
| Cerebellum/BS | 2 (7.7%) | 32 (19.2%) | 34 (17.6%) | 0.37 (0.05–2.49) | ||
| Depth of draining vein | .016 | .909 | ||||
| Periventricular | 8 (30.8%) | 19 (11.4%) | 27 (14%) | 1.0 | ||
| Subcortical | 10 (38.5%) | 60 (35.9%) | 70 (36.3%) | 0.73 (0.18–3.01) | ||
| Juxtacortical | 8 (30.8%) | 88 (52.7%) | 96 (49.7%) | 0.81 (0.16–4.09) | ||
| Direction of draining vein | .001 | .047 | ||||
| Superficial | 9 (34.6%) | 112 (67.1%) | 121 (62.7%) | 1.0 | ||
| Deep | 14 (53.8%) | 52 (31.1%) | 66 (34.2%) | 5.21 (1.22–22.2) | ||
| Both | 3 (11.6%) | 3 (1.8%) | 6 (3.1%) | 6.85 (0.84–56.0) |
Note:—BS indicates brain stem; BG, basal ganglia; P′, univariate analysis (t test or χ2 test); P″, multivariate logistic regression; brackets, 95% confidence interval for age.
↵a OR for age is expressed as the likelihood of signal abnormality with each additional year. OR for sex is expressed as the likelihood of signal abnormality for a female subject. ORs for focal atrophy and CM are expressed as the likelihood of signal abnormality in the presence of either associated abnormality. ORs for location, depth, and direction of draining vein are expressed as the likelihood of signal abnormality compared with the first DVA morphologic descriptor (eg, lobar, periventricular, superficial), defined as a baseline OR of 1.0.
↵b % is the percentage of DVAs with a certain characteristic or associated finding divided by the total number of DVAs with signal abnormality.
↵c % is the percentage of DVAs with a certain characteristic or associated finding divided by the total number of DVAs without signal abnormality.
↵d % is the percentage of DVAs with a certain characteristic or associated finding divided by the total number of DVAs.