Table 1:

Characteristics of benign and malignant ITNs that undergo surgery

Benign ITNMalignant ITNAll ITNP Value
Agea58 ± 1454 ± 1356 ± 14.3
Sex
    Female16 (67)19 (83)35 (74).3b
    Male8 (33)4 (17)12 (26)
Nodule size (in mm)
    Imaginga22 ± 1317 ± 720 ± 11.2
    PathologyNA14 ± 8NA
Imaging modality on which ITN was detected.2b,c
    CT9 (38)13 (57)22 (47)
    PET/CT4 (17)6 (26)10 (21)
    Ultrasound7 (29)2 (9)9 (19)
    MRI3 (13)1 (4)4 (9)
    Chest radiograph1 (4)01 (2)
    Echocardiogram01 (4)1 (2)
Cytology<.001b,d
    I—Nondiagnostic or unsatisfactory2 (8)1 (4)3 (6)
    II—Benign2 (8)02 (4)
    III—Atypia of undetermined significance/follicular lesion of undetermined significance10 (42)1 (4)11 (23)
    IV—Follicular neoplasm/suspicious for follicular neoplasm8 (33)1 (4)9 (19)
    V—Suspicious for malignancy2 (8)6 (26)8 (17)
    VI—Malignant014 (61)14 (30)
Total242347
  • Note:—Unless otherwise specified, data are numbers of patients, with percentages in parentheses. Percentages may not add up to 100% due to rounding.

  • a Data reported as mean ± standard deviation.

  • b Calculated with Fisher exact test.

  • c For CT versus other imaging modalities.

  • d For diagnostic categories I, II, and II versus IV, V, and VI.