Univariate analysis of the baseline variables according to the asymmetry index of cerebral veinsa
| Variable | High AI (n = 27) | Low AI (n = 27) | P Value |
|---|---|---|---|
| Mean age (yr) | 69 ± 13 | 69 ± 14 | .926 |
| Sex, female (%) | 8 (30%) | 13 (48%) | .264 |
| Serum glucose (mmol/L) | 141 ± 41 | 159 ± 72 | .268 |
| Systolic BP (mm Hg) | 156 ± 19 | 153 ± 24 | .653 |
| Time to imaging (min) | 175 ± 58 | 186 ± 68 | .514 |
| Time to treatment (min) | 222 ± 68 | 235 ± 60 | .448 |
| Baseline NIHSS score | 15 (6–18) | 9 (5–14) | .096 |
| Stroke risk factors | |||
| Atrial fibrillation (%) | 13 (48%) | 11 (41%) | .785 |
| Hypertension (%) | 20 (74%) | 18 (67%) | .766 |
| Diabetes mellitus (%) | 7 (26%) | 9 (33%) | .766 |
| Hyperlipidemia (%) | 11 (41%) | 9 (33%) | .779 |
| Current smoking (%) | 11 (41%) | 4 (15%) | .066 |
| Coronary heart disease (%) | 7 (26%) | 8 (30%) | 1.000 |
| Hyperhomocysteinemia (%) | 9 (33%) | 7 (26%) | .766 |
| White blood cell/mm3 | 7.1 ± 2.2 | 8.3 ± 2.4 | .052 |
| PT (sec) | 12.7 ± 0.9 | 12.4 ± 1.4 | .368 |
| APTT (sec) | 27.6 ± 5.6 | 25.3 ± 3.4 | .066 |
| INR | 1.06 ± 0.08 | 1.03 ± 0.12 | .325 |
| Fibrinogen level (g/L) | 7.7 ± 24.9 | 2.8 ± 0.9 | .313 |
| Serum creatinine level (mg/dL) | 0.82 ± 0.14 | 0.99 ± 0.93 | .366 |
| Serum urea nitrogen level (mg/dL) | 16.2 ± 5.1 | 16.1 ± 4.3 | .909 |
| TIMI grading | 1 (0–1) | 2 (0–3) | .002b |
| Sites of occlusion | .042b | ||
| Proximal | 22 | 14 | |
| Distal | 5 | 13 | |
| DWI lesion volume (mL) | 37 ± 57 | 15 ± 33 | .091 |
| PWI lesion volume (mL) | 120 ± 83 | 58 ± 67 | .004b |
| 24-Hour DWI lesion volume (mL) | 66 ± 82 | 35 ± 69 | .131 |
| Hemorrhagic transformation (%) | 11 (41%) | 7 (26%) | .387 |
| HI | 7 (26%) | 5 (19%) | .745 |
| PH | 4 (15%) | 2 (33%) | .669 |
| sICH | 1 (4%) | 2 (7%) | 1.000 |
| Favorable outcome | 17 (63%) | 13 (48%) | .412 |
Note:—BP indicates blood pressure; PT, prothrombin time; APTT, activated partial thromboplastin time; INR, international normalized ratio; HI, hemorrhagic infarction; PH, parenchymal hematoma; sICH, symptomatic intracerebral hemorrhage.
↵a Table cells express results in mean ± SD for normally distributed continuous variables, n (%) for dichotomous variables, and median (interquartile range) for ordinal variables and non-normally distributed continuous variables, respectively.
↵b P < .05.