Demographic data of the derivation and validation cohorts
| Derivation Cohort Healthy Volunteers | Validation Cohort | ||
|---|---|---|---|
| Healthy Volunteers | Patients with PD | ||
| No. of subjects | 113 | 50 | 30 |
| Mean age (yr) | 52.3 ± 13.1 | 54.1 ± 12.2 | 56.9 ± 10.5 |
| Male sex (No.) (%) | 58 (51.3) | 25 (50.0) | 19 (63.3) |
| Median UPDRS-III (IQR, range) | NA | NA | 29.5 (20.5–38.5; 12–47) |
| Median Hoehn and Yahr stage (IQR, range) | NA | NA | 2 (1–3; 1–3) |
| L-DOPA therapy (No.) (%) | NA | NA | 19 (63.3%) |
| DA therapy (No.) (%) | NA | NA | 15 (50.0) |
| Mean of disease duration (mo) (range) | NA | NA | 28.4 ± 12.0 (6–48) |
Note:—DA indicates dopamine agonist; IQR, interquartile range; NA, not applicable; UPDRS, Unified Parkinson's Rating Scale.