Table 1:

Baseline demographics, neurologic deficits, and hyperacute treatment status

Fibrinolysis GroupFAST GroupP Value
No. of patients2532
Age (yr) (mean)66.6 ± 10.268.3 ± 10.7.549
Male21 (84%)22 (69%).184
Hypertension11 (44%)21 (66%).103
Diabetes mellitus7 (28%)9 (28%).992
Atrial fibrillation8 (32%)11 (34%).850
NIHSS score on admission (mean)19.9 ± 8.119.8 ± 8.7.965
TOAST classification.737
    Atherosclerosis14 (56%)15 (47%)
    Cardioembolism7 (28%)12 (37%)
    Mixed or unknown4 (16%)5 (16%)
Use of intravenous rtPA7 (28%)12 (36%).35
Time from onset to puncture (min) (mean)297.0 ± 125.1281.4 ± 138.3.662
Primary endovascular treatment
    Urokinase22 (88%)
    rtPA2 (8%)
    Tirofiban1 (4%)
    Penumbra32 (100%)
Rescue treatment methods
    Stenting7 (28%)6 (18.8%)
    Tirofiban2 (8%)2 (6.3%)
    Abciximab2 (8%)
    Penumbra2 (8%)
    Solitaire3 (9.4%)
  • Note:—TOAST indicates Trial of Org 10172 in Acute Stroke Treatment.34