Table 3:

Volumetric comparisons between patients with Parkinson disease with and without mild cognitive impairment

SDGM StructuresaPD-NCI (Mean) (SD)PD-MCI (Mean) (SD)Adjusted P Value
Amygdala2.13 (0.51)2.23 (0.36).220b
Hippocampus7.65 (0.97)7.18 (0.79).198b
Nucleus accumbens0.83 (0.22)0.64 (0.19).044b
Caudate nucleus6.37 (0.76)5.96 (0.76).327b
Putamen9.51 (1.41)8.62 (1.17).058b
Pallidum3.72 (0.66)3.60 (0.84).876b
Thalamus13.94 (1.65)12.71 (1.09).025b
Normalized gray matter688.76 (34.86)661.92 (28.24).035b
Normalized white matter654.43 (41.49)633.10 (46.04).618b
  • a All volumes are reported in milliliters. Significant difference is at the P < .05 level.

  • b Analysis of variance adjusting for age, sex, education, and head size.