Univariate comparisons among patients according to FVH-DWI mismatch (n = 141)a

FVH-DWI Mismatch (n = 102)No FVH-DWI Mismatch (n = 39)P Value
Demographics/risk factors
    Age (yr)68 ± 1568 ± 14.86
    Male51 (50%)23 (59%).34
    Hypertension53 (52%)23 (59%).46
    Diabetes mellitus6 (6%)7 (18%).03
    Hyperlipidemia35 (34%)15 (38%).65
    Smoking37 (36%)11 (28%).37
Characteristics at admission
    Systolic BP (mm Hg)153 ± 24158 ± 18.31
    Diastolic BP (mm Hg)83 ± 1883 ± 17.89
    Serum glucose level (mmol/L)6.8 ± 1.67.5 ± 1.9.02
    Initial NIHSS score16 (12–20)17 (15–22).054
Initial MRI
    Time from onset to initial MRI (min)117 (87–144)122 (96–159).16
    Available PWI sequence68 (67%)26 (67%)1.00
    Terminal ICA occlusion39 (38%)11 (28%).27
    Good-to-excellent FLAIR images81 (79%)24 (61%).03
    DWI1 volume (mL)18 (8–35)108 (57–160)<.001
    PWI-DWI mismatch volume (mL)b70 (40–105)44 (33–64).03
    PWI-DWI mismatchb56 (82%)5 (19%)<.001
Cardioembolic stroke61 (60%)16 (41%).05
24-Hour evolution
    Follow-up NIHSS score11 (5–18)16 (10–22).004
    DWI2 volume (mL)d36 (19–66)161 (95–230)<.001
    Relative infarct progression (%)d195 (112–356)133 (114–165).001
    Complete recanalizationc,d29 (29%)12 (32%).77
mRS score at 3 moe3 (1–4)4 (3–6).001
mRS score ≤2 at 3 moe45 (47%)9 (24%).02
  • Note:—BP indicates blood pressure.

  • a Numbers (not %) are mean ± SD or median (interquartile range).

  • b Ninety-four patients (PWI-DWI mismatch: >6-second Tmax, Volumehypoperfusion > 1.8 × VolumeDWI1).19

  • c TICI 3.

  • d 24-hour MRI available in 138 patients.

  • e mRS score at 3 months available in 133 patients.