Univariate comparisons among patients according to FVH-DWI mismatch (n = 141)a
| FVH-DWI Mismatch (n = 102) | No FVH-DWI Mismatch (n = 39) | P Value | |
|---|---|---|---|
| Demographics/risk factors | |||
| Age (yr) | 68 ± 15 | 68 ± 14 | .86 |
| Male | 51 (50%) | 23 (59%) | .34 |
| Hypertension | 53 (52%) | 23 (59%) | .46 |
| Diabetes mellitus | 6 (6%) | 7 (18%) | .03 |
| Hyperlipidemia | 35 (34%) | 15 (38%) | .65 |
| Smoking | 37 (36%) | 11 (28%) | .37 |
| Characteristics at admission | |||
| Systolic BP (mm Hg) | 153 ± 24 | 158 ± 18 | .31 |
| Diastolic BP (mm Hg) | 83 ± 18 | 83 ± 17 | .89 |
| Serum glucose level (mmol/L) | 6.8 ± 1.6 | 7.5 ± 1.9 | .02 |
| Initial NIHSS score | 16 (12–20) | 17 (15–22) | .054 |
| Initial MRI | |||
| Time from onset to initial MRI (min) | 117 (87–144) | 122 (96–159) | .16 |
| Available PWI sequence | 68 (67%) | 26 (67%) | 1.00 |
| Terminal ICA occlusion | 39 (38%) | 11 (28%) | .27 |
| Good-to-excellent FLAIR images | 81 (79%) | 24 (61%) | .03 |
| DWI1 volume (mL) | 18 (8–35) | 108 (57–160) | <.001 |
| PWI-DWI mismatch volume (mL)b | 70 (40–105) | 44 (33–64) | .03 |
| PWI-DWI mismatchb | 56 (82%) | 5 (19%) | <.001 |
| Cardioembolic stroke | 61 (60%) | 16 (41%) | .05 |
| 24-Hour evolution | |||
| Follow-up NIHSS score | 11 (5–18) | 16 (10–22) | .004 |
| DWI2 volume (mL)d | 36 (19–66) | 161 (95–230) | <.001 |
| Relative infarct progression (%)d | 195 (112–356) | 133 (114–165) | .001 |
| Complete recanalizationc,d | 29 (29%) | 12 (32%) | .77 |
| mRS score at 3 moe | 3 (1–4) | 4 (3–6) | .001 |
| mRS score ≤2 at 3 moe | 45 (47%) | 9 (24%) | .02 |
Note:—BP indicates blood pressure.
↵a Numbers (not %) are mean ± SD or median (interquartile range).
↵b Ninety-four patients (PWI-DWI mismatch: >6-second Tmax, Volumehypoperfusion > 1.8 × VolumeDWI1).19
↵c TICI 3.
↵d 24-hour MRI available in 138 patients.
↵e mRS score at 3 months available in 133 patients.