Table 4:

Association of CBF map of pattern 1 with EGFRvIII expression in GBMa

Hyperperfusion (+)bHyperperfusion (−)cTotal
EGFRvIII (+)11112PPV: 91.67%
EGFRvIII (−)131629NPV: 55.17%
Total241741
Sensitivity45.83%
Specificity94.12%

  • Note:—PPV indicates positive predictive value; NPV, negative predictive value; +, present; −, absent.

  • ↵a Of 53 patients, 41 had EGFRvIII expression examined on postsurgical GBM tissue. Fisher exact test P value = .006.

  • ↵b CBF map with pattern 1.

  • ↵c CBF map with pattern 2.