Table 1:

Overview of 75 subjects with HHT and brain vascular malformations

CharacteristicSummarya
Demographics
    Female sex41/75 (55%)
    Age at enrollment (yr) (n = 75)36.6 ± 19.9
    Age at brain malformation diagnosis (yr) (n = 68)30.1 ± 19.7
HHT-related symptoms
    Epistaxis66/73 (90%)
    Anemia20/72 (28%)
    GI bleeding5/67 (7%)
    Pulmonary AVM45/69 (65%)
    Liver VM4/66 (6%)
HHT-causing mutation
    ALK113/45 (29%)
    Endoglin27/45 (60%)
    SMAD41/45 (2%)
    All test findings negative4/45 (9%)

  • Note:—GI indicates gastrointestinal; VM, vascular malformations.

  • ↵a Summary is the No. of observations with specified value over the total No. (and the percentage) or the mean ± SD.