Clinical characteristics of the patients
| Characteristic | True Progression (n = 24) | Pseudoprogression (n = 18) | P Value |
|---|---|---|---|
| Age (yr) | 60.50 ± 11.58 | 48.22 ± 12.54 | .002 |
| Sex | .347 | ||
| Male | 17 | 10 | |
| Female | 7 | 8 | |
| Karnofsky performance score | .371 | ||
| <70 | 4 | 1 | |
| ≥70 | 20 | 17 | |
| Surgery | .623 | ||
| Biopsy | 3 | 1 | |
| Resection | 21 | 17 | |
| Radiation dose (Gy) | 55.52 ± 8.17 | 57.83 ± 7.52 | .376 |
| Methylated MGMT promotera | 1.000 | ||
| Negative | 6 | 5 | |
| Positive | 15 | 13 |
Note:—MGMT indicates O6-methylguanine DNA methyltransferase.
↵a The promoter methylation status of MGMT, which was investigated by using the methylation-specific polymerase chain reaction technique, was documented whenever available.