Neuroanatomic regions with decreased FA in HIV-positive subjects relative to HIV-negative controlsa
| Anatomic Region | Hemisphere | MNI Coordinates (mm) | Cluster Size (mm3) | ||
|---|---|---|---|---|---|
| X | Y | Z | |||
| Genu of corpus callosum | Bilateral | −13 | 20 | 24 | 530 |
| Body of corpus callosum | Bilateral | −11 | 16 | 24 | 2228 |
| Splenium | Bilateral | −11 | −35 | 24 | 564 |
| Superior corona radiata | Left | −20 | −25 | 39 | 497 |
| Superior corona radiata | Right | 20 | −24 | 37 | 386 |
| Posterior corona radiata | Left | −21 | −28 | 34 | 262 |
| Posterior corona radiata | Right | 25 | −27 | 33 | 249 |
| Frontal WM | Left | −18 | 5 | 43 | 164 |
| Frontal WM | Right | 17 | 19 | 44 | 399 |
| Pre-/postcentral gyrus WM | Left | −21 | −25 | 42 | 269 |
| Pre-/postcentral gyrus WM | Right | 21 | −24 | 42 | 524 |
| Parietal WM | Left | −22 | −31 | 40 | 149 |
| Parietal WM | Right | 17 | −54 | 28 | 437 |
| SLF | Left | −30 | −17 | 34 | 85 |
Note:—MNI indicates Montreal Neurological Institute; SLF, superior longitudinal fasciculus.
↵a P < .05, threshold-free cluster enhancement multiple comparison–corrected. Coordinates for the peak voxels are displayed.