GLCM texture parameters, which were significantly different between patients with FA and controls for at least 1 comparison between groupsa

GLCM Distance (pixel)ParameterGroup (Mean)Comparison (P Value, Bonferroni-Corrected, t Test)
P1P2C1C2P1 × C1P1 × C2P2 × C1P2 × C2
Medulla oblongata
    1Correlation0.27 ± 0.030.25 ± 0.050.45 ± 0.090.41 ± 0.10.000b.000b.000b.000b
    1Variance11.84 ± 3.3612.80 ± 4.1417.71 ± 5.1015.60 ± 4.83.008b.188.4131.00
    1Sum average86.25 ± 3.4586.18 ± 2.62110.75 ± 5.83103.48 ± 14.32.000b.002b.000b.002b
    1Sum variance32.55 ± 9.5234.61 ± 10.8650.24 ± 16.5243.56 ± 14.79.014b.103.4841.00
    1Entropy1.46 ± 0.151.47 ± 0.072.00 ± 0.081.86 ± 0.23.000b.000b.000b.000b
    1Sum entropy0.98 ± 0.080.99 ± 0.041.36 ± 0.061.25 ± 0.17.000b.000b.000b.000b
    1Difference entropy0.71 ± 0.040.72 ± 0.040.93 ± 0.050.86 ± 0.11.000b.000b.000b.002b
    1Homogeneity0.21 ± 0.050.20 ± 0.020.27 ± 0.030.27 ± 0.04.004b.165.000b.000b
    2Correlation0.05 ± 0.050.04 ± 0.060.18 ± 0.080.17 ± 0.10.000b.001b.000b.002b
    3Correlation0.04 ± 0.050.02 ± 0.050.13 ± 0.070.14 ± 0.08.002b.004b.000b.000b
    4Correlation−0.01 ± 0.04−0.03 ± 0.050.08 ± 0.070.08 ± 0.08.004b.013b.000b.001b
    5Correlation−0.02 ± 0.03−0.03 ± 0.050.06 ± 0.070.05 ± 0.07.006b.055.008b.049b
Pons
    1Difference variance7.27 ± 2.247.56 ± 1.895.58 ± 1.455.38 ± 1.11.490.142.125.034b
  • a Both patient acquisitions were compared with both control acquisitions.

  • b Significant.