rCBV Metric | Non-PLD vs PLD (IBN) | P Value | Non-PLD vs PLD (NICE) with gvf | P Value | Non-PLD vs PLD (NICE) without gvf | P Value |
---|---|---|---|---|---|---|

Mean | r = 0.87 | <.001 | r = 0.11 | .54 | r = 0.43 | .01 |

ρ = 0.86 | <.001 | ρ = 0.42 | .02 | ρ = 0.62 | <.001 | |

Mode | r = 0.78 | <.001 | r = 0.44 | .01 | r = 0.51 | .01 |

ρ = 0.76 | <.001 | ρ = 0.65 | <.001 | ρ = 0.65 | <.001 | |

% < 1.75 | r = 0.93 | <.001 | r = 0.55 | <.001 | r = 0.59 | <.001 |

ρ = 0.91 | <.001 | ρ = 0.61 | <.001 | ρ = 0.60 | <.001 | |

FTB | r = 0.96 | <.001 | r = 0.79 | <.001 | r = 0.70 | <.001 |

ρ = 0.94 | <.001 | ρ = 0.72 | <.001 | ρ = 0.71 | <.001 |

**Note:**—gvf indicates γ variate fitting.↵a NICE calculations were performed with and without gvf. IBN modeling shows substantially higher correlation between PLD and non-PLD metrics (compared with NICE), suggesting higher rCBV accuracy in the absence of PLD correction. Statistical significance is

*P*value < .05.