Effect of clinical variables on sensitivity and specificity of localization and lateralization in patients with single adenomas
| Localization | Lateralization | |||||
|---|---|---|---|---|---|---|
| Variable: Yes | Variable: No | P Value | Variable: Yes | Variable: No | P Value | |
| BMI ≥ 30 (na = 166) | ||||||
| Sensitivity, % | 48.4 | 56.0 | .328 | 69.2 | 84.0 | .022 |
| Specificity, % | 87.9 | 82.2 | .081 | 59.3 | 69.3 | .180 |
| Diabetes (n = 213) | ||||||
| Sensitivity, % | 45.2 | 53.3 | .407 | 71.0 | 75.3 | .628 |
| Specificity, % | 88.2 | 85.7 | .456 | 61.3 | 63.7 | .799 |
| Prior neck surgery (n = 201) | ||||||
| Sensitivity, % | 55.0 | 53.0 | .870 | 75.0 | 75.7 | .947 |
| Specificity, % | 91.7 | 85.6 | .99 | 75.0 | 63.5 | .278 |
| Hypothyroidism (n = 212) | ||||||
| Sensitivity, % | 43.8 | 54.4 | .268 | 59.4 | 77.8 | .049 |
| Specificity, % | 86.5 | 85.7 | .872 | 46.9 | 66.1 | .046 |
| Thyroid goiter or nodules (n = 218) | ||||||
| Sensitivity, % | 46.4 | 57.0 | .143 | 69.6 | 78.5 | .170 |
| Specificity, % | 87.4 | 85.7 | .540 | 58.0 | 67.1 | .199 |
| Radioactive iodine therapy (n = 218) | ||||||
| Sensitivity, % | 42.9 | 53.6 | .602 | 57.1 | 75.8 | .360 |
| Specificity, % | 81.0 | 86.3 | .596 | 42.9 | 64.5 | .291 |
| Gland weight ≥1 g (n = 221) | ||||||
| Sensitivity, % | 69.8 | 50.0 | .014 | 90.7 | 71.9 | .001 |
| Specificity, % | 85.3 | 86.5 | .736 | 72.1 | 62.4 | .213 |
| Preoperative PTH level ≥ 150 (n = 221) | ||||||
| Sensitivity, % | 53.8 | 53.1 | .911 | 81.3 | 71.5 | .087 |
| Specificity, % | 84.6 | 87.7 | 0.274 | 64.8 | 64.6 | 0.973 |
| Preoperative calcium level ≥11 (n = 222) | ||||||
| Sensitivity, % | 62.7 | 49.7 | 0.070 | 80.6 | 73.5 | 0.242 |
| Specificity, % | 86.1 | 86.2 | 0.957 | 67.2 | 63.2 | 0.572 |
Note:—BMI indicates body mass index; PTH, parathyroid hormone.
↵a Total number of patients in whom this variable could be confirmed on retrospective chart review.