Analysis of the relationship between baseline perfusion parameters and EGFRvIII mutation status

Perfusion ParameteraEGFRvIII Status (Median, Range)P ValueAUC
Negative (n = 58)Positive (n = 24)
rVPmean3.6 (1.5–18.1)9.3 (2.9–29.3)<.0010.818
rVP90%tile5.1 (1.6–19.1)10.7 (4.1–30.2)<.0010.833
rVP75%tile4.2 (1.6–18.4)9.2 (3.5–28.1)<.0010.821
rKtransmean3.7 (1.1–20.3)6.5 (1.7–22.4).0080.688
rKtrans90%tile4.8 (1.5–22.6)7.6 (2.1–31.8).020.669
rKtrans75%tile4.2 (1.4–19.7)6.8 (1.9–24.7).0070.692
  • Note:—AUC indicates area under the curve in the ROC analysis.

  • a All values are relative ratios normalized to tumor/contralateral normal tissue.