Radiologic characteristics of patients with or without cSS
| Type of MBs | No. of Patients (%) | P Value | ||
|---|---|---|---|---|
| Total | Any cSS | No cSS | ||
| No. of patients | 347 | 12 | 335 | |
| Lobar MBs | ||||
| Frontal | 69 (19.9%) | 7 (58.3%) | 62 (18.5%) | .003 |
| Temporal | 65 (18.7%) | 8 (66.7%) | 57 (17.0%) | <.001 |
| Parietal | 78 (22.5%) | 7 (58.3%) | 71 (21.2%) | .007 |
| Occipital | 63 (18.2%) | 7 (58.3%) | 56 (16.7%) | .002 |
| Deep MBs | ||||
| Thalamoganglionic | 62 (17.9%) | 3 (25.0%) | 59 (17.6%) | .456 |
| Brain stem | 32 (9.2%) | 3 (25.0%) | 29 (8.7%) | .088 |
| Cerebellum | 48 (13.8%) | 3 (25.0%) | 45 (13.4%) | .222 |
| Topographic distribution of MBs | ||||
| Strictly lobar | 71 (20.5%) | 6 (50.0%) | 65 (19.4%) | .020 |
| Strictly deep | 10 (2.9%) | 0 (0%) | 10 (3.0%) | 1.00 |
| Mixed | 79 (22.8%) | 5 (41.7%) | 74 (22.1%) | .154 |
| No MBs | 187 (53.9%) | 1 (8.3%) | 186 (55.5%) | .002 |
| Lacunar infarcts | 71 (20.5%) | 6 (50.0%) | 65 (19.4%) | .020 |
| WMH (mean)a | 1.5 ± 0.8 | 1.9 ± 0.8 | 1.4 ± 0.8 | .053 |
| 0 | 32 (9.2%) | 0 (0%) | 32 (9.6%) | |
| 1 | 166 (47.8%) | 4 (33.3%) | 162 (48.4%) | |
| 2 | 107 (30.8%) | 5 (41.7%) | 102 (30.4%) | |
| 3 | 42 (12.1%) | 3 (25.0%) | 39 (11.6%) | |
Note:—WMH indicates white matter hyperintensities.
↵a WMH were graded according to the scale of Fazekas et al17: 0, absent; 1, punctate; 2, early confluent; and 3, confluent.