Demographic, clinical, and imaging characteristics of index and control casesa
| Factor | Index (n = 6) | Control (n = 25) | Group Effect (P Value) |
|---|---|---|---|
| Age (yr) | 39 (27–67) | 35 (18–59) | .39 |
| Sex (% female) | 67 | 68 | .67 |
| Anterior territory CBF baseline (mL/100 g/min) | 36.6 (33.3–57.9) | 50.2 (31.2–62.9) | .14 |
| Anterior territory CBF post-ACZ (mL/100 g/min) | 34.3 (23.4–64.5) | 63.7 (39.0–74.3) | .007 |
| Anterior change CBF (CVR) (%) | −0.4 (−38.7–16.6) | 26.3 (−8.2–60.5) | .003 |
| Posterior territory CBF baseline (mL/100 g/min) | 41.7 (33.4–48.8) | 38.8 (27.1–54.5) | .36 |
| Posterior territory CBF post-ACZ (mL/100 g/min) | 54.2 (31.7–64.7) | 55.6 (38.2–72.2) | .39 |
| Posterior change CBF (CVR) (%) | 31.9 (−19.1–55.4) | 39.1 (0.9–117.7) | .16 |
| Volume of acute infarcts following surgery (mL) | 95.0 (17.0–181.0) | 0 | NA |
| Patients with acute (DWI+) infarcts on preop MRI (%) | 4 (66.7%) | 0 (0%) | NA |
Note:—ACZ indicates acetazolamide; preop, preoperative; NA, not applicable; DWI+, DWI with positive findings.
↵a Values are median (range) where applicable.