Table 2:

Bivariate Pearson correlation coefficients between MRI measures and multivariable linear regression of R2* with QSM and R2 using zero intercept (R2* = a1QSM + a2R2)

GPPutamenCaudateAputPput
MRI
    R2 (QSM)0.51a0.72b0.52a0.67a0.72a
    R2* (QSM)0.73b0.81b0.47a0.71a0.83a
    R2* (R2)0.55b0.78b0.48a0.75a0.75a
    CSF-T2WI (T2)0.71b0.85b0.59b0.79b0.87b
Multivariable linear regression for R2*
    a10.28 ± 0.04b0.22 ± 0.04b0.15 ± 0.06c0.21 ± 0.05a0.25 ± 0.04b
    a21.05 ± 0.14b1.31 ± 0.07b1.42 ± 0.16b1.42 ± 0.08b1.08 ± 0.10b
FractionalQSM: 47%QSM: 23%QSM: 20.0%QSM: 18%QSM: 36%
ContributionsR2: 53%R2: 77%R2: 80.0%R2: 82%R2: 64%
  • Note:—Aput indicates cognitive anterior part of putamen, region predominantly connected to frontal cortex; Pput, motor posterior part of putamen, region predominantly connected to sensorimotor cortex.

  • a P < 10−3.

  • b P < 10−6.

  • c P = .02.