RCI Baseline–Month 12 | Patients on Natalizumab | Patients on IFNb/GA | P Value |
---|---|---|---|
Symbol Digit Modalities Test | −0.02 ± 0.68 | −0.04 ± 0.77 | .993 |
SPART-total | 0.18 ± 1.46 | −0.49 ± 1.42 | .432 |
SPART-delayed | 0.54 ± 1.69 | 0.06 ± 1.99 | .629 |
VLGT–immediate recall | −0.67 ± 0.88 | 0.20 ± 1.03 | .024a |
VLGT–short-term free recall | −0.15 ± 1.01 | 0.06 ± 0.75 | .575 |
VLGT–long-term free recall | −0.21 ± 1.36 | 0.47 ± 0.84 | .211 |
WLG–Animals | 0.15 ± 0.90 | −0.40 ± 0.81 | .185 |
WLG–Professions | −0.19 ± 0.88 | 0.04 ± 1.17 | .835 |
WLG–4 letter “M” words | −0.61 ± 0.88 | −0.36 ± 1.08 | .129 |
Digit Span Forward | −0.01 ± 0.87 | 0.06 ± 0.85 | .842 |
Digit Span Backward | −0.31 ± 0.89 | −0.34 ± 1.42 | .572 |
TMT–Letter-Number Switching | 0.41 ± 3.23 | 0.59 ± 2.91 | .922 |
Stroop-interference | −1.00 ± 2.14 | −0.78 ± 1.63 | .595 |
Note:—SPART indicates Spatial Recall Task; VLGT, Verbal Memory and Learning Task; WLG, Word List Generation; TMT, Trail-Making Test.
↵a A significant difference between the patient groups.