Demographic and clinical characteristics of study sample
| Demographics/Characteristics | |
|---|---|
| No. of subjects | 24 |
| No. of lesions | 306 |
| Lesions per subject analyzed (median) (range) | 12 (2–29) |
| Age (mean) (SD) (yr) | 44.3 (10.0) |
| Sex (No.) (%) | |
| Female | 12 (50%) |
| Male | 12 (50%) |
| Disease duration (mean) (SD) (yr) | 11.2 (7.6) |
| Clinical phenotype (No.) (%) | |
| Relapsing-remitting | 21 (88%) |
| Secondary-progressive | 2 (8%) |
| Primary-progressive | 1 (4%) |
| On MS treatment (No.) (%) | 19 (79%) |
| EDSS score (median) (range) | 3.0 (1.5–6.5) |
| MFIS score (mean) (SD) | 37.7 (19.3) |
| 9-HPT, dominant hand (mean) (SD) | 23.0 (6.6) seconds |
| 9-HPT, nondominant hand (mean) (SD) | 27.7 (17.9) seconds |
| Timed 25-ft walk (mean) (SD) | 5.3 (2.4) seconds |
| PASAT-3 score (mean) (SD) | 46.3 (9.8) |
| MSFC z score (mean) (SD) | −0.27 (1.54) |
Note:—9-HPT indicates Nine Hole Peg Test; PASAT-3, Paced Auditory Serial Addition Test, 3-second delay.