Sensitivity, specificity, PPV, and NPV for NCCT/CTA and CTP (based on perfusion parameters) in the detection of acute lacunar infarct
| Imaging Modality | Sensitivity | Specificity | PPV | NPV |
|---|---|---|---|---|
| NCCT/CTA | 2.7% (P < .0001) | 100.0% (P < .0001) | 100.0% (P < .99) | 68.1% (P < .0001) |
| CBF | 24.3% (P < .003) | 97.4% (P < .0001) | 81.8% (P = .07) | 72.8% (P < .0001) |
| CBV | 18.9% (P = .0002) | 98.7% (P < .0001) | 87.5% (P = .07) | 71.4% (P < .0001) |
| TTP | 48.7% (P < .99) | 97.4% (P < .0001) | 90.0% (P = .0004) | 80.0% (P < .0001) |
| MTT | 35.1% (P = .10) | 99.7% (P < .0001) | 92.9% (P = .002) | 76.0% (P < .0001) |
Note:—NPV indicates negative predictive value; PPV, positive predictive value.