Table 2:

Percentage changes of V_MY, V_EPW, R1, R2, and PD in plaques and periplaque white matter relative to normal-appearing white matter^{^a}

	V_MY (%)	V_EPW (%)	R1 (%)	R2 (%)	PD (%)
Plaques	−61.59 ± 20.28^{^b}	13.82 × 10³ ± 49.47 × 10^{3^b}	−35.23 ± 13.93^{^b}	−21.06 ± 11.39^{^b}	23.37 ± 10.30^{^b}
PWM	−10.51 ± 11.41^{^c}	51.33 × 10² ± 155.31 × 10^{2^c}	−6.08 ± 8.66^{^c}	−4.79 ± 6.79^{^c}	3.37 ± 4.24^{^b}

↵a Values are mean ± SD. Of the 135 ROIs, 39 were discarded after calculating the percentage change of V_EPW relative to NAWM because the V_EPW of these ROIs was equivalent to zero in NAWM.
↵b P < .001 in the percentage change for plaques relative to NAWM for comparison between each pair of metrics, except between R2 and PD (P = .31). Statistical analysis was performed for absolute values.
↵c P < .001 in the percentage change for PWM relative to NAWM between V_EPW and other metrics, and between V_MY and R2 or PD, P < .05 between V_MY and R1, and P > .05 between R2 and R1 (.31) or PD (.30). Statistical analysis was performed for absolute values.