Table 1:

Success of VBD formation in C57BL/6J and SV129 mouse strainsa

Follow-Up Time Point (Days)C57BL/6JSV129P Value
Total No.No. SuccessfulSuccess Rate (95% CI)Total No.No. SuccessfulSuccess Rate (95% CI)
3740.57 (0.18–0.90)500.00 (0.00–0.52)
7860.75 (0.35–0.97)300.00 (0.00–0.71)
14740.57 (0.18–0.90)600.00 (0.00–0.46)
28540.80 (0.28–1.0)500.00 (0.00–0.52)
Total No.27180.67 (0.46–0.84)1900.00 (0.00–0.18)<.001
  • a Successful VBD was defined as the percentage increase in basilar artery diameter of ≥50% and a tortuosity index of ≥10. The number and proportion of mice showing successful VBD for each strain and time point are displayed. Ninety-five percent Clopper-Pearson CIs are displayed for each estimate. Proportion of successes was compared between strains using the Fisher exact test.