Characteristics of patients with and without the IPTSV signa
| IPTSV (n = 35) | Non-IPTSV (n = 74) | Test Value | PValue | |
|---|---|---|---|---|
| Age (yr) | 68.9 ± 12.8 | 68.0 ± 13.0 | t = −0.34 | .74 |
| Female (No.) (%) | 10 (28.6) | 30 (40.5) | χ2 = 1.47 | .29 |
| Risk factors | ||||
| Hypertension (No.) (%) | 28 (80.0) | 47 (63.5) | χ2 = 3.01 | .12 |
| Diabetes mellitus (No.) (%) | 9 (25.7) | 16 (21.6) | χ2 = 0.23 | .63 |
| Atrial fibrillation (No.) (%) | 13 (37.1) | 29 (39.2) | χ2 = 0.04 | 1.00 |
| Smoking (No.) (%) | 18 (51.4) | 25 (33.8) | χ2 = 3.10 | .10 |
| Previous stroke/TIA (No.) (%) | 6 (17.1) | 11 (14.9) | χ2 = 0.10 | .78 |
| Large-artery occlusion (No.) (%) | 26 (74.3) | 34 (45.9) | χ2 = 7.02 | .007e |
| Baseline SBP (mm Hg) | 153.7 ± 20.0 | 153.7 ± 23.4 | t = 0.01 | .99 |
| Baseline DBP (mm Hg) | 83.1 ± 10.7 | 86.8 ± 18.3 | t = 1.32 | .19 |
| ONT (min) | 266.9 ± 68.6 | 229.0 ± 73.8 | t = −2.56 | .01e |
| Baseline glucose level (mmol/L) | 7.7 ± 2.1 | 7.9 ± 2.9 | t = 0.42 | .67 |
| Baseline NIHSS score | 13.0 (7.0–18.0) | 7.0 (3.8–11.5) | Z = −2.87 | .004e |
| Baseline diffusion lesion volume (mL) | 5.9 (0.9–65.9) | 2.0 (0–15.1) | Z = −2.74 | .006e |
| Baseline hypoperfusion volume (mL) | 111.2 (44.0–173.3) | 29.3 (5.0–71.4) | Z = −4.04 | <.001e |
| 24-Hr CT scan (No.) (%)b | 1 (2.9) | 3 (4.3) | χ2 = 0.096 | 1.00 |
| Proportion of penumbral tissue loss (%)c | 32.6 (0.6–100.0) | 4.5 (0–27.4) | Z = −2.89 | .004e |
| Infarct volume at 24 hours (mL) | 40.8 (7.5–113.6) | 5.0 (1.0–19.6) | Z = −4.27 | <.001e |
| Poor outcome (No.) (%)d | 22 (62.9) | 19 (25.7) | χ2 = 14.00 | <.001e |
Note:—SBP indicates systolic blood pressure; DBP, diastolic blood pressure; ONT, onset-to-needle time.
↵a Table cells express results in mean ± SD for normally distributed continuous variables, No. (%) for dichotomous variables, and median (interquartile range) for ordinal variables and non-normally distributed continuous variables, respectively.
↵b Twenty-four-hour CT scan: the proportion of patients imaged with CT rather than MRI for 24-hour follow-up imaging.
↵c Proportion of Penumbral Tissue Loss = 100 × (Posttreatment Infarct Volume − Pretreatment Infarct Volume)/(Pretreatment Hypoperfusion Volume − Pretreatment Infarct Volume).
↵d Poor outcome = 3-month modified Rankin Scale score ≥ 2.
↵e P < .05.