Table 2:

Diagnostic performance of individual parameters in the detection of glioma recurrencea

rCBVmean ≥ 1.709ADCmean ≤ 1507Cho/Cr ≥ 1.405TBRmax ≥ 1.579TBRmean ≥ 1.179
Sensitivity82.8%86.7%100.0%93.3%90.0%
Specificity63.6%54.5%66.7%72.7%81.8%
PPV85.7%83.9%88.9%90.3%93.1%
NPV58.3%60.0%100.0%80.0%75.0%
Accuracy77.5%78.0%90.9%87.8%87.8%
AUC±SE0.68 ± 0.1110.752 ± 0.0150.861 ± 0.080.827 ± 0.0780.888 ± 0.059
P value.008b.013b<.001b<.001b<.001b
  • Note:—PPV indicates positive predictive value; NPV, negative predictive value; SE, standard error.

  • a The ADCmean value is expressed as ×10−6mm2/s and rCBVmean. Cho/Cr, TBRmax, and TBRmean are ratios and hence unitless. P values mentioned are generated while calculating the AUC from the ROC analysis.

  • b P values of rCBVmean, ADCmean, Cho/Cr, TBRmax, and TBRmean are <.05 and hence are statistically significant. P value reflects the significance of the ROC analysis of individual parameters represented in the table.