Measurement of TV, sensitivity, specificity, PPV, NPV, YI, and AUC of ADCmin values, rADC, rCBVmax, cMRI, DWI + DSC-PWI, and cMRI+ DWI + DSC-PWI for assessing the IDH status of grade II and III astrocytomas
| TV | Sensitivity (%) | Specificity (%) | PPV (%) | NPV (%) | YI | AUC (95% CI) | |
|---|---|---|---|---|---|---|---|
| ADCmin | 1.01 | 76.92 | 82.61 | 91.20 | 60.50 | 0.60 | 0.87 (0.71–0.96) |
| rADC | 1.60 | 84.62 | 73.91 | 88.30 | 67.30 | 0.59 | 0.84 (0.68–0.94) |
| rCBVmax | 2.35 | 100.00 | 60.87 | 85.60 | 100.00 | 0.61 | 0.82 (0.66–0.93) |
| cMRI | 88.24 | 52.00 | 88.50 | 44.30 | 0.40 | 0.78 (0.63–0.89) | |
| DWI + DSC-PWI | 100.00 | 65.22 | 87.00 | 100.00 | 0.65 | 0.88 (0.54–0.84) | |
| cMRI+ DWI + DWI-PWI | 92.31 | 91.30 | 96.10 | 83.60 | 0.84 | 0.92 (0.78–0.98) |
Note:—TV indicates threshold values; PPV, positive predictive value; NPV, negative predictive value; YI, Youden Index; AUC, area under the curve.