Characteristics of preterm samples and term reference samplea
| Acquired Medical Factors | From Birth to Early MRI (n = 83) | From Birth to Term MRI (n = 77) | Term Reference Sample (n = 38) |
|---|---|---|---|
| Patent ductus arteriosus | 39 (47%) | 36 (47%) | |
| IVH | 17 (20%) | 16 (21%) | |
| IVH grade 3 or 4 | 4 (5%) | 4 (5%) | |
| Periventricular leukomalacia | 2 (2%) | 2 (3%) | |
| Hydrocephalus | 2 (2%) | 2 (3%) | |
| NEC diagnosed or suspected | 3 (4%) | 2 (3%) | |
| Confirmed sepsis | 3 (4%) | 2 (3%) | |
| Total parenteral nutrition (days) | 11 [8–14], 0–30 | 11 [8–14], 0–30 | |
| Postnatal corticosteroids | 14 (17%) | 14 (18%) | |
| Ventilation (days) | 3 [0–12], 0–48 | 2 [0–12], 0–48 | |
| CPAP (days) | 15 [7–25], 0–47 | 30 [7–47], 0–81 | |
| Oxygen therapy (hr) | 12 [1–125], 0–1515, n = 69 | 29 [2–370], 0–3912, n = 67 | |
| 36-week PMA O2 requirement | 23 (30%) | ||
| PMA at MRI (wk) | 32+2 (1+3), 29+3–35+2 | 40+6 (1+3), 38+3–46+4 | 41+3 (1), 39+2–44 |
| Weight at MRI (g) | 1500 (352), 883–2715 | Early MRI 1505 (359), 883–2715 | 3428 (378), 2500–4200, n = 31 |
| Term MRI 3127 (627), 1900–5150 |
Note:—IVH indicates intraventricular hemorrhage; NEC, necrotizing enterocolitis; CPAP, continuous positive airway pressure.
↵a Data are No. (%), median [IQR] or mean (SD), range. Early MRI, 29 to 35 weeks PMA; term MRI, 40 to 42 weeks PMA.