Table 2:

Parameter estimates calculated with a mixed-effects model of BTR and baseline brain temperature as a function of CVR

	CVR				CVR²				Intercept
	Coefficient	F	df^a	P Value	Coefficient	F	df^a	P Value	Coefficient	F	df^a	P Value^b
BTR
CVR_BOLD	−0.052	74.1	1, 513	<.001	0.0068	57.5	1, 619	<.001	0.031	6.0	1, 35	.02
CVR_ASL	0.0018	1.2	1, 8.0	.30	–	–	–	–	−0.069	205	1, 3.8	<.001
CVR_BOLD < 70^c	−0.096	59.7	1, 97	<.001	0.024	25.0	1, 128	<.001	0.031	2.8	1, 11	.12
CVR_BOLD ≥ 70^c	0.0070	5.5	1, 200	.02	–	–	–	–	−0.081	46.0	1, 51	<.001
CVR_ASL < 30^d	0.0018	1.1	1, 7.4	.33	–	–	–	–	−0.068	183.2	1, 69	<.001
CVR_ASL ≥ 30^d	0.0014	12.1	1, 47	.001	–	–	–	–	−0.10	33.5	1, 44	<.001
T_pre^e (°C)
CVR_BOLD	0.59	7.0	1, 598	.008	−0.13	14.8	1, 630	<.001	37.5	4871	1, 27	<.001
CVR_ASL	−0.039	0.9	1, 7.3	.39	–	–	–	–	38.4	8655	1, 6.0	<.001
CVR_BOLD < 70^c	2.1	19.5	1, 139	<.001	−0.65	12.9	1, 150	<.001	37.1	1810	1, 17	<.001
CVR_BOLD ≥ 70^c	−0.38	10.7	1, 429	.001	–	–	–	–	39.0	4575	1, 28	<.001
CVR_ASL < 30^d	−0.049	1.1	1, 6.8	.34	–	–	–	–	38.5	12,953	1, 6.5	<.001
CVR_ASL ≥ 30^d	0.0026	0.01	1, 198	.91	–	–	–	–	37.5	1094	1, 27	<.001

↵a df calculated with the Satterthwaite approximation are reported as numerator, denominator.
↵b P value represents the significance of a nonzero intercept.
↵c CVR_BOLD values thresholded to 70% of the subject-wise mean contralateral value.
↵d CVR_ASL values thresholded to 30% augmentation.
↵e T_pre is the baseline brain temperature.