ROC curve analyses of CBFmax and rCBFmax in discriminating high- and low-grade gliomas
| Parameters/Patients | AUC | Youden Index | Cutoff Value | Sensitivity (%) | Specificity (%) | PPV (%) | NPV (%) | Accuracy (%) |
|---|---|---|---|---|---|---|---|---|
| CBFmax | ||||||||
| All | 0.828 | 0.690 | 91 mL/100 g/min | 84.4 | 84.6 | 95.0 | 61.1 | 84.5 |
| Excludeda | 0.859 | 0.829 | 91 mL/100 g/min | 82.9 | 100 | 100 | 56.3 | 86.0 |
| rCBFmax | ||||||||
| All | 0.863 | 0.668 | 1.19 | 82.2 | 84.6 | 94.9 | 57.9 | 82.8 |
| Excludeda | 0.916 | 0.805 | 1.22 | 80.5 | 100 | 100 | 52.9 | 84.0 |
Note:—AUC indicates area under the curve; PPV, positive predictive value; NPV, negative predictive value.
↵a With oligodendrogliomas and anaplastic oligodendrogliomas excluded.