Cerebral blood flow values in patients and controlsa
| ROI | Sections | Voxelsb | CBF, Repeatabilityc | CBF (Mean) (SD) (mL/100 g/min) | P Valued | |
|---|---|---|---|---|---|---|
| Patients | Controls | |||||
| Cerebellum | 2 | 924 (144) | 0.92 | 20.7 (9.3) | 27.2 (7.0) | .006 |
| MFC | 3 | 133 (30) | 0.90 | 24.9 (5.6) | 27.4 (5.1) | .23 |
| Lentiform nucleus | 1 | 115 (15) | 0.75 | 20.4 (2.7) | 25.0 (4.0) | <.001e |
| MTL | 1 | 114 (15) | 0.86 | 30.4 (5.6) | 31.7 (3.8) | .86 |
| HCC | 2 | 1350 (459) | 0.72 | 22.5 (5.5) | 21.6 (3.0) | .47 |
| Pons | 3 | 68 (17) | 0.90 | 22.0 (7.0) | 24.1 (5.3) | .19 |
| SMA | 2 | 130 (18) | 0.72 | 25.1 (5.1) | 25.2 (3.7) | .93 |
| Thalamus | 2 | 116 (19) | 0.92 | 26.8 (10.2) | 34.1 (5.6) | <.001e |
| Frontal WM | 2 | 41 (8) | 0.91 | 11.0 (5.0) | 10.7 (2.2) | .76 |
| Lateral WM | 2 | 136 (33) | 0.89 | 12.2 (3.0) | 13.8 (1.7) | .014 |
| Superior WM | 2 | 67 (7) | 0.88 | 14.2 (5.0) | 12.6 (2.5) | .17 |
| Periventricular WM | 1 | 186 (15) | 0.88 | 8.0 (2.5) | 13.1 (3.1) | <.001e |
Note:—HCC indicates high-convexity cortex; MFC, medial frontal cortex; MTL, medial temporal lobe; SMA, supplementary motor area.
↵a Data are mean with SD in parentheses unless otherwise indicated.
↵b Mean (SD) voxels in each ROI in patients.
↵c Repeatability of perfusion measurements between the 2 baseline investigations using the intraclass correlation coefficient.
↵d Unadjusted P values tested with the paired-samples t test.
↵e Significant after Holm-Bonferroni correction.