Table 1:

Comparison of patients with low and high HIRa

CharacteristicsLow HIR (n = 122)High HIR (n = 122)P Value
    Age70 (56–79)71 (60–79).446
    Male (No.) (%)55 (45)83 (68)<.001
    Hypertension (No.) (%)b68 (57)66 (55).685
    Diabetes mellitus (No.) (%)b12 (10)20 (17).142
    Hyperlipidemia (No.) (%)b31 (26)40 (33).251
    Current smoking (No.) (%)c23 (20)25 (21).771
    Systolic BP (mm Hg)149 (139–163)156 (139–173).141
    Diastolic BP (mm Hg)82 (71–89)81 (70–93).990
    Serum glucose (mmol/L)d6.1 (5.4–7.0)6.5 (5.5–7.9).038
    NIHSSb score11 (7–17)16 (11–21)<.001
Baseline MRI
    Onset-to-MRI time (min)112 (86–153)112 (84–156).838
    Proximal occlusion (No.) (%)81 (66)80 (66).893
    DWI1 volume (mL)8 (4–19)41 (16–96)<.001
    Tmax >6-sec volume (mL)44 (17–85)115 (56–147)<.001
    Tmax >10-sec volume (mL)9 (2–22)52 (27–75)<.001
    PWI-DWI mismatch (No.) (%)85 (70)59 (48)<.001
    FVH score (No.) (%).016e
        0–16 (5)13 (11)
        2–330 (25)33 (27)
        4–554 (44)59 (48)
        6–732 (26)17 (14)
24-hr follow-up
    NIHSS scoref6 (2–15)14 (7–20)<.001
    ENI (No.) (%)f51 (42)27 (22).001
    DWI2 volume (Ml)18 (9–45)87 (33–161)<.001
    Infarct growth (Ml)6 (1–26)29 (10–75)<.001
    Complete recanalization (No.) (%)40 (33)45 (37).502
3-mo mRS ≤ 1 (No.) (%)g49 (45)25 (21)<.001
3-mo mRS ≤ 2 (No.) (%)g63 (58)51 (44).033
  • Note:—BP indicates blood pressure; ENI, early neurologic improvement.

  • a Unless specified, numbers are median (interquartile range).

  • b Missing data for 4 patients.

  • c Missing data for 9 patients.

  • d Missing data for 13 patients.

  • e P for Trend.

  • f Missing data for 5 patients.

  • g Missing data for 18 patients.