Summary of the main perfusion MRI study findings in MS
| Active Lesions | Chronic Lesions | NAWM | Deep Gray Matter | |
|---|---|---|---|---|
| CBF | ↑ (Compared with NAWM) | ↓ (Compared with NAWM and WM in controls) | ↓ (Compared with WM in controls) | ↓ (Compared with controls) |
| CBV | ↑ (Compared with NAWM) | ↓ (Compared with NAWM) | ↓ (Compared with WM in controls) | ↓ (Compared with controls) |
| MTT | No significant change | ↑ (Compared with WM in controls) | ↑ (Compared with WM in controls) | ↑ (Compared with controls) |
Note:—↑ indicates increased; ↓, decreased.