Table 4:

MRI features among telomere maintenance glioblastoma subtypes

MRI FeatureTelomere Maintenance Subtype
ALT+/M−ALT−/M−ALT−/M+Pearson χ2 and P ValuesaALT+/M+
No. of patients2692566
Regular margin, % (no.)58 (15)30 (28)30 (17)7.3, .02633 (2)
Fungating margin, % (no.)19 (5)53 (49)61 (34)12.8, .00267 (4)
Cystic component, % (no.)39 (10)24 (22)11 (6)8.5, .01450 (3)
Radiologic necrosis, % (no.)58 (15)73 (67)86 (48)7.7, .02183 (5)
Extensive PTE, % (no.)23 (6)23 (21)45 (25)8.6, .01417 (1)
Multifocal lesion, % (no.)15 (4)12 (11)23 (13)NS33 (2)
Hemorrhage, % (no.)8 (2)20 (18)7 (4)NS3 (2)
  • Note:—NS indicates not significant.

  • a Statistical comparisons were made between 3 groups: ALT+/M−, ALT−/M−, and ALT−/M+.