Patient and tumor characteristics
| Primary HNSCC | rHNSCC and sHNSSC after Treatment | |
|---|---|---|
| Total No. of patients | 100 | |
| Total No. of tumors | 103 | 38a |
| Female (No.) (%) | 22 (22%) | |
| Male (No.) (%) | 78 (78%) | |
| Mean age (yr) | 59.3 ± 11.3 | 61.5 ± 11.1 |
| Treatment modalities in pHNSCC (No. of patients) | NA | |
| RTH alone | 52 | |
| Operation followed by RTH | 48 | |
| Median interval (quartile 1–quartile 3) between end of RTH and rHNSCC/sHNSCC (mo) | NA | 14 (4.5–51) |
| Tumor location (No. of tumor sites) (%) | ||
| Nasopharynx | 7 (6.8%) | 1 (2.6%) |
| Oral cavity | 22 (21.3%) | 13 (34.2%) |
| Oropharynx | 38 (36.9%) | 8 (21.1%) |
| Hypopharynx | 12 (11.6%) | 5 (13.1%) |
| Larynx | 19 (18.5%) | 6 (15.8%) |
| Paranasal sinuses | 4 (3.9%) | 2 (5.3%) |
| Base of the skull | 0 (0%) | 3 (7.9%) |
| Unknown primary tumor | 1 (1%) | 0 (0%) |
| T classificationb | ||
| Tx | 1 (1%) | 0 (0%) |
| Tis | 1 (1%) | 1 (2.6%) |
| T1 | 14 (13.6%) | 3 (7.9%) |
| T2 | 30 (29.1%) | 7 (18.4%) |
| T3 | 25 (24.3%) | 6 (15.8%) |
| T4 | 32 (31.0%) | 21 (55.3%) |
| N classificationb | ||
| N0 | 31 (30.1%) | 26 (68.4%) |
| N1 | 20 (19.4%) | 5 (13.2%) |
| N2 | 45 (43.7%) | 6 (15.8%) |
| N3 | 6 (5.8%) | 1 (2.6%) |
| Nx | 1 (1%) | 0 (0%) |
| M classificationb | ||
| Mx | 7 (6.8%) | 0 (0%) |
| M0 | 94 (91.3%) | 36 (94.7%) |
| M1 | 2 (1.9%) | 2 (5.3%) |