Partial correlations of blood BHB concentration (mg/dL) and brain metabolite ratios derived from 1H-MRS, using patient age in months as a covariate
| Group | BHB/Cr | BHB/Cho | BHB/NAA | BHB/Lac | Cho/Cr | NAA/Cr | NAA/Cho | Lac/NAA | Lac/Cr |
|---|---|---|---|---|---|---|---|---|---|
| Lag ≤14 d (n = 13) | |||||||||
| R | .871 | .898 | .886 | .507 | −.287 | −.645 | −.540 | .376 | .253 |
| Significance | .000 | .000 | .000 | .092 | .367 | .024 | .070 | .228 | .428 |
| Lag ≤30 d (n = 23) | |||||||||
| R | .803 | .814 | .807 | .538 | −.165 | −.553 | −.443 | .421 | .334 |
| Significance | .000 | .000 | .000 | .010 | .463 | .008 | .039 | .051 | .128 |
| Lag ≤120 d (n = 31) | |||||||||
| R | .790 | .802 | .781 | .484 | −.312 | −.658 | −.515 | .523 | .423 |
| Significance | .000 | .000 | .000 | .008 | .099 | .000 | .004 | .004 | .022 |
| All (N = 49) | |||||||||
| R | .579 | .588 | .584 | .393 | −.170 | −.387 | −.312 | .290 | .162 |
| Significance | .000 | .000 | .000 | .006 | .254 | .007 | .033 | .048 | .278 |
Note:—Lac indicates lactate.