Table 1:

Patient demographics with respect to molecular groups

ParametersWNT (n = 15) (%)SHH (n = 26) (%)Group 3 (n = 29) (%)Group 4 (n = 49) (%)Total (n = 119) (%)P
Sex.02a
    Male7 (46.7)13 (50)20 (69)39 (80)79 (66.4)
    Female8 (53.3)13 (50)9 (31)10 (20)40 (33.6)
Age at diagnosis (yr)b8.7 (3.1)6.2 (4.6)6.1 (3.8)8.1 (3.2)7.3 (3.8)<.0001a
Histology.02a
    LCA1 (6.7)9 (34.6)13 (44.8)7 (14.3)30 (25.2)
    Classic14 (93.3)8 (30.8)15 (51.7)39 (79.6)76 (63.9)
    Desmoplastic0 (0)9 (34.6)1 (3.5)3 (6.1)13 (10.9)
  • Note:—LCA indicates large-cell anaplastic.

  • a Statistically significant.

  • b Mean with SDs.