Regional MPF (%) | Second Trimester Fetuses (18–26.5 GW, n = 23) | Third Trimester Fetuses (27–38 GW, n = 18) | Adults (n = 3) |
---|---|---|---|
Brain stem | 3.30 ± 0.43 | 4.28 ± 0.45b | 10.60 ± 0.38 |
Cerebellum | 2.32 ± 0.41c | 3.23 ± 0.53b,c | 12.28 ± 0.63 |
Thalamus | 3.03 ± 0.48d | 3.74 ± 0.46b,c,d | 8.62 ± 0.21 |
Frontal WM | 2.62 ± 0.34c,e | 2.36 ± 0.33c,d,e | 12.63 ± 0.54 |
Temporal WM | 2.61 ± 0.17c,e | 2.63 ± 0.26c,d,e | 13.20 ± 0.24 |
Occipital WM | 2.54 ± 0.30c,e | 2.41 ± 0.27c,d,e | 12.11 ± 0.45 |
Note:—GW indicates gestational weeks.
↵a Fetal data were compared between trimesters and structures using repeated-measures ANOVA. P values are Bonferroni-corrected for multiple pair-wise comparisons. No statistical comparisons were performed for the adult data.
↵b Significantly different from the second trimester (P < .001).
↵c Significantly different from the brain stem within the same trimester (P < .001).
↵d Significantly different from the cerebellum within the same trimester (P < .001).
↵e Significantly different from the thalamus within the same trimester (P < .001).