Patient and deep brain stimulation characteristics and outcomesa
| Variable | Summary (N = 11) |
|---|---|
| Patient characteristics | |
| Age at DBS (mean) (range) (yr) | 62 (49–73) |
| Male sex (No.) (%) | 10 (90.9%) |
| Disease duration (mean) (range) (yr) | 9 (6–16) |
| Handedness (right) (No.) (%) | 10 (90.9%) |
| Deep brain stimulation information | |
| Volume of tissue activated (mm3) | |
| Caudate | |
| No. (%) of patients with values of >0 | 0 (0.0%) |
| Median (minimum, maximum) | 0.0 (0.0, 0.0) |
| GPe | |
| No. (%) of patients with values of >0 | 11 (100.0%) |
| Median (minimum, maximum) | 19.3 (0.8, 78.4) |
| M1 | |
| No. (%) of patients with values of >0 | 8 (72.7%) |
| Median (minimum, maximum) | 3.6 (0.0, 42.9) |
| PPN | |
| No. (%) of patients with values of >0 | 1 (9.1%) |
| Median (minimum, maximum) | 0.0 (0.0, 7.9) |
| PFC | |
| No. (%) of patients with values of >0 | 2 (18.2%) |
| Median (minimum, maximum) | 0.0 (0.0, 5.5) |
| Putamen | |
| No. (%) of patients with values of >0 | 2 (18.2%) |
| Median (minimum, maximum) | 0.0 (0.0, 38.8) |
| SMA/PMC | |
| No. (%) of patients with values of >0 | 6 (54.6%) |
| Median (minimum, maximum) | 4.8 (0.0, 46.5) |
| STN | |
| No. (%) of patients with values of >0 | 0 (0.0%) |
| Median (minimum, maximum) | 0.0 (0.0, 0.0) |
| SN | |
| No. (%) of patients with values of >0 | 8 (72.7%) |
| Median (minimum, maximum) | 5.8 (0.0, 36.3) |
| Thalamus | |
| No. (%) of patients with values of >0 | 1 (9.1%) |
| Median (minimum, maximum) | 0.0 (0.0, 0.5) |
| Outcomes | |
| Preoperative UPDRS III score (range) | 42 (27–55) |
| 6-Month follow-up UPDRS III score (range) | 21 (13–40) |
| Change in UPDRS III score (preoperative minus 6-month follow-up) (range) | 15 (−12–31) |
Note:—PFC indicates prefrontal cortex; PPN, pedunculopontine nucleus.
↵a The sample median (minimum, maximum) is given for continuous variables.