Table 2:

Summary of the multivariate CPH models with age and surgical extent (subtotal, gross total resection) as covariates

EdgeTimePFS P ValueHR95% CIOS P ValueHR95% CI
EC100%Postbevacizumab.009a0.370.18–0.78.046b0.420.18–0.98
EC75%Postbevacizumab.013b0.330.13–0.79.041b0.340.12–0.96
EC50%Postbevacizumab.015b0.290.10–0.78.026b0.250.07–0.85
EC25%Postbevacizumab.018b0.210.05–0.77.022b0.160.03–0.77
FLAIRVOLPostbevacizumab.8721.0001.000–1.000.2041.0001.000–1.000
CEVOLPostbevacizumab.7581.0001.000–1.000.2581.0001.000–1.000
ΔEC100%Pre- and postbevacizumab.018b2.811.92–6.65.033b2.981.09–8.16
ΔEC75%Pre- and postbevacizumab.039b2.751.05–7.19.0503.060.99–9.39
ΔEC50%Pre- and postbevacizumab.0582.910.96–8.08.0543.540.97–12.88
ΔEC25%Pre- and postbevacizumab.0673.740.090–15.42.0564.760.95–23.64
ΔFLAIRVOLPre- and postbevacizumab.3601.0001.000–1.000.4871.0001.000–1.000
ΔCEVOLPre- and postbevacizumab.9511.0001.000–1.000.9261.0001.000–1.000
  • Note:—CPH indicates Cox proportional hazards; HR, hazard ratio.

  • a P < .01.

  • b P < .05.