Demographic and clinical characteristics of study participants
| MS (n = 176) | HC (n = 47) | P | |
|---|---|---|---|
| Age at baseline (mean) (yr) | 46.95 ± 11.247 | 45.96 ± 14.47 | .616 |
| Female/male; % female | 130:46; 73.9 | 34:13; 72.3 | .853 |
| Disease duration (mean) (yr) | 15.16 ± 9.87 | – | – |
| CIS (No.) (%) | 16, 9.1 | – | – |
| RRMS (No.) (%) | 114, 64.8 | – | – |
| PPMS (No.) (%) | 7, 4.0 | – | – |
| SPMS (No.) (%) | 39, 22.2 | – | – |
| EDSS (median) (IQR) | 2.5, 1.5–4.5 | – | – |
| White (No.) (%) | 167, 94.9 | 43, 91.5 | .480 |
| Hispanic/Latino (No.) (%) | 3, 1.7 | 0, 0.0 | – |
| Black/African American (No.) (%) | 3, 1.7 | 3, 6.4 | .110 |
| Asian (No.) (%) | 1, 0.6 | 1, 2.1 | .378 |
Note:—CIS indicates clinically isolated syndrome; IQR, interquartile range; RRMS, relapsing-remitting MS; EDSS, Expanded Disability Status Scale; –, not applicable/not evaluable; PPMS, primary-progressive MS; SPMS, secondary-progressive MS.