Table 1:

MR imaging features and IDH-mutation and 1p/19q codeletion status

IDH Wild- TypeIDH-MutantPIDH-Mutant, Non-1p/19q CodeletedIDH-Mutant, 1p/19q CodeletedP
MR imaging features (No.) (%)
    T2 signal intensitiesa
        >Gray matter13 (22.4%)30 (43.5%).012c21 (48.8%)9 (34.6%).248
        >Mixed45 (77.6%)39 (56.5%)22 (51.2%)17 (65.4%)
T2 homogeneitya
    Homogeneous6 (10.3%)14 (20.3%).12510 (23.3%)4 (15.4%).544
    Heterogeneous52 (89.7%)55 (79.7%)33 (76.7%)22 (84.6%)
Margin
    Well-defined32 (54.2%)27 (38.0%).06520 (44.4%)7 (26.9%).143
    Mixed27 (45.8%)44 (62.0%)25 (55.6%)19 (73.1%)
Edema
    No-to-minimal20 (33.9%)57 (79.2%)<.001c38 (82.6%)19 (73.1%).339
    Mild-to-marked39 (66.1%)15 (20.8%)8 (17.4%)7 (26.9%)
Enhancing patternb
    None/minimally enhancing4 (7.0%)30 (42.3%)<.001c19 (41.3%)11 (44.0%).826
    Enhancing55 (93.2%)41 (56.9%)27 (58.7%)14 (56.0%)
Proportion of enhancing areab
    <50%14 (23.7%)63 (88.7%)<.001c40 (87.0%)23 (92.0%).704
    ≥50%45 (76.3%)8 (11.3%)6 (13.0%)2 (8.0%)
Cystic area
    Presence5 (8.5%)28 (39.4%).013c26 (56.5%)17 (65.4%).461
    Absence54 (91.5%)43 (59.7%)20 (43.5%)9 (34.6%)
Necrotic areab
    Presence49 (83.1%)16 (22.5%)<.001c38 (82.6%)17 (68.0%).159
    Absence10 (16.9%)55 (77.5%)8 (17.4%)8 (32.0%)
rADCmean (median)1.11.6<.001c1.71.5.071
rADCmin (median)0.91.4<.001c1.41.3.178
rADCmax (median)1.31.8<.001c1.91.7.106
  • a There were 4 cases lacking T2 MR images.

  • b One case in the IDH-mutant group lacked postcontrast studies.

  • c Statistically significant (P < .05).