Correlations between clivus size and clinical parameters
| Variable | Size of Clivus | P Value | |
|---|---|---|---|
| Normal | <2.5 SDs Compared with Controls | ||
| Truncating mutation (total n = 19)a | |||
| + | 5 | 12 | .12 |
| − | 2 | 0 | |
| Presence of choanal atresia | |||
| + | 1 | 4 | .33 |
| − | 8 | 10 | |
| Presence of coloboma (total n = 22)b | |||
| + | 4 | 8 | .36 |
| − | 5 | 5 | |
| Presence of cleft (total n = 22)b | |||
| + | 3 | 2 | .61 |
| − | 6 | 11 | |
| Verloes6 criteria satisfiedc | |||
| + | 4 | 8 | 1.00 |
| − | 2 | 3 | |
| Blake et al5 criteria satisfiedc | |||
| + | 3 | 5 | 1.00 |
| − | 4 | 8 | |
Note:—+ indicates yes; −, no.
↵a Four patients had a splice site mutation and could not be classified as either truncating or nontruncating.
↵b For 1 patient, no data regarding presence of coloboma were available. For 1 patient, no information regarding cleft lip/palate was available.
↵c See also On-line Table 1.