Basic demographics, symptoms, MRI findings, and modified Rankin Scale scores of patients with neurosarcoidosis
| Characteristics | Total (%) | DMVE (+) (%) | DMVE (−) (%) | P Value |
|---|---|---|---|---|
| No. | 21 | 7 | 14 | |
| Age (mean ± SD) (yr) | 46 ± 14 | 45 ± 13 | 47 ± 16 | .813 |
| Sex (M/F) | 10/11 | 6/1 | 4/10 | .013a |
| Symptoms | ||||
| Headache | 8 (38%) | 4 (57%) | 4 (29%) | .346 |
| Vision loss | 5 (24%) | 1 (14%) | 4 (29%) | .624 |
| Seizure | 3 (14%) | 0 (0%) | 3 (21%) | .521 |
| Extremity weakness | 3 (14%) | 1 (14%) | 2 (14%) | 1 |
| Cranial neuropathy | 2 (10%) | 0 (0%) | 2 (14%) | .533 |
| Gait instability | 3 (14%) | 2 (29%) | 1 (7%) | .247 |
| Bowel/bladder dysfunction | 4 (19%) | 3 (43%) | 1 (7%) | .088 |
| Others | 4 (19%) | 1 (14%) | 3 (21%) | |
| Intracranial hemorrhage | ||||
| Microhemorrhage | 7 (33%) | 5 (71%) | 2 (14%) | .009a |
| Macrohemorrhage | 1 (5%) | 1 (14%) | 0 (0%) | .147 |
| Enhancing disease | ||||
| Leptomeningeal | 13 (62%) | 4 (57%) | 9 (64%) | .751 |
| Pachymeningeal | 8 (38%) | 3 (43%) | 5 (36%) | .751 |
| Perivascular | 3 (14%) | 3 (43%) | 0 (0%) | .008a |
| Venous thrombosis | 2 (10%) | 1 (14%) | 1 (7%) | .599 |
| Hydrocephalus | 6 (29%) | 4 (57%) | 2 (14%) | .040a |
| Modified Rankin Scale score (mean) | ||||
| At initial MRI (n = 20) | 3.2 ± 0.75 | 2.1 ± 1.5 | .125 | |
| At follow-up (n = 18) | 2.4 ± 1.1 | 1.5 ± 1.1 | .167 |
↵a Statistically significant.