Table 2:

Comparison between CCT images alone and CCT-plus-BSI images of skull base invasiona

ParameterTPbTNbFNbFPbSensitivity (%)P ValueSpecificity (%)P ValuePPV (%)NPV (%)
All sites
    CCT alone66155182579 (68–87).016c86 (80–90).010c7390
    CCT-plus-BSI781726893 (85–97)96 (91–98)9197
Sphenoid body
    CCT alone18144882 (60–95).62564 (41–83).039d6978
    CCT-plus-BSI20212191 (71–99)95 (77–100)9591
    CCT alone11229255 (32–77).031d92 (73–99)1.0008571
    CCT-plus-BSI17223285 (62–97)92 (73–99)8988
Base of the pterygoid process
    CCT alone176011094 (73–100).15786 (75–93).012c6398
    CCT-plus-BSI186802100 (81–100)97 (90–100)90100
Petrous apex
    CCT alone20594583 (63–95).22192 (83–97).3068094
    CCT-plus-BSI23611396 (79–100)95 (87–99)8898
  • Note:—FN indicates false-negative findings; FP, false-positive findings; NPV, negative predictive value; PPV, positive predictive value; TN, true-negative findings; TP, true-positive findings.

  • a Numbers in parentheses are 95% confidence intervals.

  • b Data are numbers of findings.

  • c P < .05, according to the generalized estimating equations that accounted for the multiple observations within patients.

  • d P < .05, as determined with the McNemar test.