Treatment-related outcomes after Y-stent-assisted coiling of bifurcation aneurysms
| Variables | Results of Systematic Review and Meta-Analysis | No. of Articles | Statistic (95% CI) (I2) |
|---|---|---|---|
| Angiographic outcomes | |||
| Rate of successful stent deployment | 550/569 = 97% | 20 | (96–99) (I2 = 0%) |
| Immediate aneurysm occlusion rate (RR 1–2) | 352/468 = 82.2% | 15 | (71.4–93) (I2 = 92%) |
| Long-term aneurysm occlusion rate (RR 1–2) | 564/598 = 95.4% | 24 | (93.7–97) (I2 = 0%) |
| Aneurysm recanalization | 20/496 = 3% | 19 | (1.5–4.5) (I2 = 0%) |
| Recanalization among anterior circulation | 2/89 = 2% | 9 | (0.9–9) (I2 = 0%) |
| Recanalization among posterior circulation | 11/130 = 4% | 12 | (2–9) (I2 = 0%) |
| Mean size of recanalized vs nonrecanalized aneurysms (mm) | 11 ± 2.4 vs 7 ± 1.18 | 7 | |
| Rate of retreatment of recanalized aneurysms | 10/20 = 50% | 19 | (29–70) |
| Treatment-related complications and clinical outcomes | |||
| Overall treatment-related complications | 63/614 = 8.9% | 23 | (5.8–12.1) (I2 = 44%) |
| Periprocedural/early complications (within 30 days) | 46/574 = 6.7% | 21 | (4–9) (I2 = 35%) |
| Delayed complications (after 30 days) | 9/574 = 2.1% | 21 | (1–3) (I2 = 0%) |
| Transient complications | 33/540 = 6.5% | 20 | (2.2–6) (I2 = 21%) |
| Symptomatic complications without permanent deficits | 22/540 = 3% | 20 | (1.3–4) (I2 = 35%) |
| Permanent complications | 18/540 = 2.4% | 20 | (1.2–3.7) (I2 = 0%) |
| Treatment-related mortality | 5/668 = 1.1% | 23 | (0.3–1.9) (I2 = 0%) |
| Overall rate of good neurologic outcome | 291/317 = 94.5% | 15 | (92–97) (I2 = 7%) |
| Type of complications | |||
| Thromboembolic complications | 44/594 = 6.5% | 22 | (3–7.6) (I2 = 29%) |
| Hemorrhagic complications | 11/594 = 2% | 22 | (0.7–3) (I2 = 0%) |
| Acute in-stent thrombosis | 20/577 = 2.1% | 22 | (1.6–6) (I2 = 0%) |
| Aneurysm rupture after treatment | 0/650 = 0% | 22 | |
| Chronic in-stent stenosis | 10/295 = 2.3% | 11 | (0.6–4) (I2 = 0%) |
Note:—RR indicates Raymond-Roy grade.