The PSNR and NRMSE of synthetic FLAIR and DL-FLAIR images against conventional FLAIR images in various regions^{^a}

	Synthetic FLAIR Images	DL-FLAIR Images
GM
PSNR	27.16 ± 0.54^{^b,^c}	34.03 ± 1.33^{^b,^c} (+25.31%)
NRMSE	0.47 ± 0.039^{^b,^c}	0.33 ± 0.028^{^b,^c} (−30.44%)
WM
PSNR	29.51 ± 0.44^{^b,^c}	35.45 ± 1.48^{^b,^c} (+20.14%)
NRMSE	0.37 ± 0.025^{^b,^c}	0.27 ± 0.024^{^b,^c} (−27.32%)
CSF
PSNR	34.83 ± 1.37^{^b,^c}	40.47 ± 1.37^{^b,^c} (+16.21%)
NRMSE	0.29 ± 0.027^{^b,^c}	0.21 ± 0.017^{^b,^c} (−27.36%)
Aggregate intracranial tissues
PSNR	29.79 ± 0.71^{^b}	35.90 ± 1.21^{^b} (+20.54%)
NRMSE	0.38 ± 0.024^{^b}	0.27 ± 0.016^{^b} (−28.66%)

↵a Values are means ± SD. Percentage changes in the PSNR and NRMSE for DL-FLAIR vs synthetic FLAIR images are in parentheses.
↵b P < .001 for synthetic FLAIR vs DL-FLAIR images.
↵c P < .001 for GM vs WM, GM vs CSF, and WM vs CSF.