The frequencies of spinal MRI findings and associations with monophasic/relapsing disease
| MRI Findings | Monophasic Disease (n = 50) (n) (%) | Recurrent Disease (n = 27) (n) (%) | P Value | Unadjusted OR (95% CI) |
|---|---|---|---|---|
| LETM (n = 42) (54.5%) | 22 (44%) | 20 (74.1%) | .022a | 3.63 (1.30–10.14) |
| Multifocal lesions (n = 16) (22.5%) | 9/44 (20.5%) | 7 (25.9%) | .808 | 1.36 (0.44–4.21) |
| Distribution | .304 | |||
| Cervical (n = 21) (27.3%) | 14 (28%) | 7 (25.9%) | ||
| Cervicothoracic (n = 14) (18.2%) | 6 (12%) | 8 (29.6%) | ||
| Thoracic (n = 35) (45.5%) | 25 (50%) | 10 (37%) | ||
| Holocord (n = 7) (9.1%) | 5 (10%) | 2 (7.4%) | ||
| Brain stem extension (n = 5) (6.5%) | 1/46 (2.2%) | 4/25 (16%) | .049a | 8.57 (0.90–81.46) |
| Location | .521 | |||
| Gray matter (n = 3) (3.9%) | 3 (6%) | 0 | ||
| Gray + white matter (n = 65) (84.4%) | 42 (84%) | 23 (85.2%) | ||
| White matter (n = 9) (11.7%) | 5 (10%) | 4 (14.8%) | ||
| >1/2 of the cord area (n = 55) (71.4%) | 33 (66%) | 22 (81.5%) | .242 | 2.26 (0.73–7.04) |
| Cord expansion (n = 48) (62.3%) | 26 (52%) | 22 (81.5%) | .021a | 4.06 (1.32–12.42) |
| T1 hypointensity (n = 23) (30.3%) | 11/49 (22.4%) | 12 (44.4%) | .089 | 2.76 (1.01–7.61) |
| BSLs (n = 27) (35.1%) | 12 (24%) | 15 (55.6%) | .012a | 3.95 (1.45–10.74) |
| Owl's eyes sign (n = 2) (2.6%) | 2 (4%) | 0 | .539 | 0.58 (0.06–5.88) |
| Enhancement (n = 48) (62.3%) | 26 (52%) | 22/26 (84.6%) | .011a | 5.07 (1.52–16.87) |
| Brain involvement (n = 17) (27%) | 11/43 (25.6%) | 6/20 (30%) | .950 | 1.24 (0.38–4.04) |
↵a Significant.